Dr. Mendelsohn has been on the forefront of the advanced techniques for conditions of the mouth and throat, establishing one of the largest surgical volumes on the west coast of transoral robotic cancer surgery (TORS), sialendoscopy, and hypoglossal nerve stimulator (Inspire) implantation surgery.

His undergraduate study was in Biology, graduating Magna Cum Laude with a Bachelor of Arts from Yeshiva University in New York before attending the David Geffen School of Medicine at UCLA. During his time in medical school, his research focused on voice and throat disorders, taking an extra academic year to study the treatment of spasmodic dysphonia (voice spasms). He went on to complete his residency in Otolaryngology-Head & Neck Surgery at UCLA and was recognized for his high level of teaching as Chief Resident.

Following his surgical residency, Dr. Mendelsohn received fellowship training in Laryngology at the UCLA Voice Center, where he studied the endoscopic surgery for voice and airway disorders. He proceeded to travel abroad to receive fellowship training in Trans-Oral Laser Surgery (TLM) and Trans-Oral Robotic Surgery (TORS) at the Université Catholique de Louvain in Yvoir, Belgium. Dr. Mendelsohn has also served as a Staff Surgeon in the Division of Head & Neck Surgery at the Veterans Affairs (VA) Medical Center of Greater Los Angeles and Volunteer Staff Surgeon at Walter Reed National Military Medical Center.

His research has been nationally and internationally recognized, particularly in the area of studying the underlying mechanisms of voice production to preserve its function following endoscopic cancer surgical resections. Dr. Mendelsohn is a leader in endoscopic and minimally invasive head and neck surgery.